Publications

Brown, K. A.; Chen, B.; Guardado-Alvarez, T. M.; Lin, Z.; Hwang, L.; Ayaz-Guner, S.; Jin, S.; Ge, Y. A Photocleavable Surfactant for Top-Down Proteomics, Nature Methods 16, 417-420 (2019)

Martin-Garrido A, Biesiadecki BJ., Salhi HE., Shaifta Y., Dos Remedios CG., Ayaz-Guner S., Cai W., Ge Y., Avkiran M., Kentish JC. Monophosphorylation of cardiac troponin-I at Ser-23/24 is sufficient to regulate cardiac myofibrillar Ca2+ sensitivity and calpain-induced proteolysis. J Biol Chem.  293(22):8588-8599 (2018)

Hwang L.; Guardado-Alvarez T.; Ayaz-Guner S.; Ge Y.; Song J.; A Family of Photolabile Nitroveratryl-Based Surfactants That Self-Assemble into Photodegradable Supramolecular Structures, Langmuir, 2016, 32 (16), 3963–3969

Cai W.; Guner H.; Gregorich Z.R.; Chen A.J.; Ayaz-Guner S.; Peng Y.; Valeja S.G.; Liu X.; Ge Y.; MASH Suite Pro: A Comprehensive Software Tool for Top-Down Proteomics, Molecular & Cellular Proteomics, 2016, 15 (2), 703-714.

Yu D; Peng Y.; Ayaz-Guner S.; Gregorich Z.R.; Ge Y.; Comprehensive Characterization of AMP-Activated Protein Kinase Catalytic Domain by Top-Down Mass Spectrometry, J. Am. Soc. Mass Spectrom., 2016, 27 (2), 220-232.

Ayaz-Guner, S*.; Chen, Y*.; Peng, Y.; Lane N. M.; Locher M. R.; Kohmoto T.; Larsson L.; Moss R. L.; Ge, Y.; Effective top-down LC/MS+ method for assessing actin isoforms as a potential cardiac disease marker, Analytical Chemistry, 2015 87 (16), 8399-8406 .(* Equal contribution)

Hwang L.; Ayaz-Guner S.; Gregorich Z.R.; Valeja S.; Chang Y.; Cai W.; Jin S.; Ge Y.Highly Specific Enrichment of Phosphoproteins Using Functionalized Multivalent Nanoparticles, J. Am. Chem. Soc., 2015, 87, 5363-5371.

Ayaz-Guner, S.*; Peng, Y.*; Yu, D.; Ge, Y. Top-down mass spectrometry of cardiac myofilament proteins in health and disease, Proteomics Clin. Appl., 2014, 8(7-8), 554-568. .(* Equal contribution)

Zhao, Z., Wang, L., Wen, Z., Ayaz-Guner, S., Wang, Y., Ahlquist, P., and Xu, W.  Systematic analyses of the cytotoxic effects of compound 11a, a putative synthetic agonist of photoreceptor-specific nuclear receptor (PNR), in cancer cell lines, Plos One, 2013, 8(9):e75198.

Guy, M. J.; Chen, Y.; Clinton, L.; Zhang, H.; Zhang, J.; Dong, X.; Xu, Q.; Ayaz-Guner, S.; Ge, Y. The impact of antibody selection on the detection of cardiac troponin I, Clin. Chim. Acta., 2013, 420, 82-88. 

Zhang, J.; Ayaz-Guner, S.; Dong, X.; Xu, Q.; Guner, H.; Ge, Y. Phosphorylation, but not alternative splicing or proteolytic degradation, is conserved in human and mouse cardiac troponin T, Biochemistry, 2011, 50, 6081-6092.

Ayaz-Guner, S.; Zhang, J.; Li, L.; Walker, J. W.; Ge, Y. In vivo phosphorylation site mapping in mouse cardiac troponin I by high resolution top-down electron capture dissociation mass spectrometry: Ser22/23 are the only sites basally phosphorylated, Biochemistry, 2009, 48, 8161-8170.